diff --git a/include/config/battle.h b/include/config/battle.h
index 242e4bea68..16b4ac9b64 100644
--- a/include/config/battle.h
+++ b/include/config/battle.h
@@ -124,6 +124,7 @@
 #define B_WIDE_GUARD                GEN_LATEST // In Gen5 only, Wide Guard has a chance to fail if used consecutively.
 #define B_QUICK_GUARD               GEN_LATEST // In Gen5 only, Quick Guard has a chance to fail if used consecutively.
 #define B_IMPRISON                  GEN_LATEST // In Gen5+, Imprison doesn't fail if opposing pokemon don't have any moves the user knows.
+#define B_TAUNT_ME_FIRST            GEN_LATEST // In Gen5+, Taunt does not block Me First.
 #define B_ALLY_SWITCH_FAIL_CHANCE   GEN_LATEST // In Gen9+, using Ally Switch consecutively decreases the chance of success for each consecutive use.
 #define B_SKETCH_BANS               GEN_LATEST // In Gen9+, Sketch is unable to copy more moves than in previous generations.
 #define B_KNOCK_OFF_REMOVAL         GEN_LATEST // In Gen5+, Knock Off removes the foe's item instead of rendering it unusable.
diff --git a/include/constants/generational_changes.h b/include/constants/generational_changes.h
index 84b9da76b1..8a8a31e830 100644
--- a/include/constants/generational_changes.h
+++ b/include/constants/generational_changes.h
@@ -115,6 +115,7 @@
     F(B_WIDE_GUARD,                wideGuard,               (u32, GEN_COUNT - 1)) \
     F(B_QUICK_GUARD,               quickGuard,              (u32, GEN_COUNT - 1)) \
     F(B_IMPRISON,                  imprison,                (u32, GEN_COUNT - 1)) /* TODO: use in tests */ \
+    F(B_TAUNT_ME_FIRST,            tauntMeFirst,            (u32, GEN_COUNT - 1)) \
     F(B_ALLY_SWITCH_FAIL_CHANCE,   allySwitchFailChance,    (u32, GEN_COUNT - 1)) \
     F(B_SKETCH_BANS,               sketchBans,              (u32, GEN_COUNT - 1)) /* TODO: use in tests */ \
     F(B_KNOCK_OFF_REMOVAL,         knockOffRemoval,         (u32, GEN_COUNT - 1)) /* TODO: use in tests */ \
diff --git a/src/battle_util.c b/src/battle_util.c
index f0b4925229..8535da5493 100644
--- a/src/battle_util.c
+++ b/src/battle_util.c
@@ -1474,7 +1474,10 @@ u32 TrySetCantSelectMoveBattleScript(u32 battler)
         }
     }
 
-    if (GetActiveGimmick(battler) != GIMMICK_Z_MOVE && gDisableStructs[battler].tauntTimer != 0 && IsBattleMoveStatus(move))
+    if (GetActiveGimmick(battler) != GIMMICK_Z_MOVE
+        && gDisableStructs[battler].tauntTimer != 0
+        && IsBattleMoveStatus(move)
+        && (GetConfig(B_TAUNT_ME_FIRST) < GEN_5 || moveEffect != EFFECT_ME_FIRST))
     {
         if ((GetActiveGimmick(battler) == GIMMICK_DYNAMAX))
             gCurrentMove = MOVE_MAX_GUARD;
@@ -1709,7 +1712,10 @@ u32 CheckMoveLimitations(u32 battler, u8 unusableMoves, u16 check)
         else if (check & MOVE_LIMITATION_TORMENTED && move == gLastMoves[battler] && gBattleMons[battler].volatiles.torment == TRUE)
             unusableMoves |= 1u << i;
         // Taunt
-        else if (check & MOVE_LIMITATION_TAUNT && gDisableStructs[battler].tauntTimer && IsBattleMoveStatus(move))
+        else if (check & MOVE_LIMITATION_TAUNT
+              && gDisableStructs[battler].tauntTimer
+              && IsBattleMoveStatus(move)
+              && (GetConfig(B_TAUNT_ME_FIRST) < GEN_5 || moveEffect != EFFECT_ME_FIRST))
             unusableMoves |= 1u << i;
         // Imprison
         else if (check & MOVE_LIMITATION_IMPRISON && GetImprisonedMovesCount(battler, move))
@@ -2249,7 +2255,12 @@ static enum MoveCanceler CancelerVolatileBlocked(struct BattleContext *ctx)
 
 static enum MoveCanceler CancelerTaunted(struct BattleContext *ctx)
 {
-    if (GetActiveGimmick(ctx->battlerAtk) != GIMMICK_Z_MOVE && gDisableStructs[ctx->battlerAtk].tauntTimer && IsBattleMoveStatus(ctx->currentMove))
+    enum BattleMoveEffects moveEffect = GetMoveEffect(ctx->currentMove);
+
+    if (GetActiveGimmick(ctx->battlerAtk) != GIMMICK_Z_MOVE 
+        && gDisableStructs[ctx->battlerAtk].tauntTimer 
+        && IsBattleMoveStatus(ctx->currentMove)
+        && (GetConfig(B_TAUNT_ME_FIRST) < GEN_5 || moveEffect != EFFECT_ME_FIRST))
     {
         gProtectStructs[ctx->battlerAtk].unableToUseMove = TRUE;
         CancelMultiTurnMoves(ctx->battlerAtk, SKY_DROP_ATTACKCANCELER_CHECK);
diff --git a/test/battle/move_effect/me_first.c b/test/battle/move_effect/me_first.c
index 8ccaa324ef..48f8d179be 100644
--- a/test/battle/move_effect/me_first.c
+++ b/test/battle/move_effect/me_first.c
@@ -82,6 +82,37 @@ SINGLE_BATTLE_TEST("Me First can be selected if users holds Assault Vest")
     }
 }
 
+SINGLE_BATTLE_TEST("Me First can be selected under Taunt in Gen5+")
+{
+    u32 gen = 0;
+
+    PARAMETRIZE { gen = GEN_4; }
+    PARAMETRIZE { gen = GEN_5; }
+
+    GIVEN {
+        WITH_CONFIG(B_TAUNT_ME_FIRST, gen);
+        PLAYER(SPECIES_WOBBUFFET) { Speed(100); Moves(MOVE_ME_FIRST, MOVE_TACKLE); }
+        OPPONENT(SPECIES_WOBBUFFET) { Speed(50); Moves(MOVE_TAUNT, MOVE_TACKLE); }
+    } WHEN {
+        TURN { MOVE(player, MOVE_TACKLE); MOVE(opponent, MOVE_TAUNT); }
+        if (gen >= GEN_5) {
+            TURN { MOVE(player, MOVE_ME_FIRST); MOVE(opponent, MOVE_TACKLE); }
+        } else {
+            TURN {
+                MOVE(player, MOVE_ME_FIRST, allowed: FALSE);
+                MOVE(player, MOVE_TACKLE);
+                MOVE(opponent, MOVE_TACKLE);
+            }
+        }
+    } SCENE {
+        ANIMATION(ANIM_TYPE_MOVE, MOVE_TAUNT, opponent);
+        if (gen >= GEN_5)
+            ANIMATION(ANIM_TYPE_MOVE, MOVE_ME_FIRST, player);
+        else
+            ANIMATION(ANIM_TYPE_MOVE, MOVE_TACKLE, player);
+    }
+}
+
 SINGLE_BATTLE_TEST("Me First deducts power points from itself, not the copied move")
 {
     ASSUME(GetMovePP(MOVE_ME_FIRST) == 20);